Jian Yan Selected Research

VGX-3100

1/2018	Clinical and Immunologic Biomarkers for Histologic Regression of High-Grade Cervical Dysplasia and Clearance of HPV16 and HPV18 after Immunotherapy.
11/2015	Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.

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Jian Yan Research Topics

Disease

40	Neoplasms (Cancer) 06/2022 - 01/2002
20	Infections 01/2021 - 04/2007
11	Human Influenza (Influenza) 01/2018 - 04/2007
8	Inflammation (Inflammations) 01/2020 - 01/2012
7	Carcinogenesis 01/2017 - 04/2003
5	Hypoxia (Hypoxemia) 06/2022 - 01/2016
5	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 02/2014
5	Hepatocellular Carcinoma (Hepatoma) 05/2015 - 01/2012
4	Communicable Diseases (Infectious Diseases) 01/2019 - 09/2012
4	Arthritis (Polyarthritis) 02/2013 - 04/2011
3	Placental Insufficiency 10/2019 - 07/2017
3	Uterine Cervical Dysplasia 01/2018 - 10/2012
3	Liver Cirrhosis (Hepatic Cirrhosis) 08/2013 - 01/2012
3	Influenza in Birds (Avian Flu) 05/2009 - 04/2007
3	Phototoxic Dermatitis (Phototoxicity) 09/2005 - 08/2004
2	COVID-19 12/2022 - 01/2020
2	Retinoblastoma (Glioblastoma, Retinal) 06/2022 - 04/2020
2	Erythema 01/2022 - 11/2015
2	Neoplasm Metastasis (Metastasis) 01/2022 - 02/2002
2	Glioma (Gliomas) 01/2021 - 01/2019
2	Emerging Communicable Diseases (Emerging Infectious Diseases) 01/2021 - 05/2014
2	Lymphoma (Lymphomas) 01/2021 - 12/2018
2	Fever (Fevers) 01/2021 - 01/2015
2	Lung Neoplasms (Lung Cancer) 04/2020 - 04/2018
2	Carcinoma (Carcinomatosis) 12/2018 - 08/2013
2	Chronic Disease (Chronic Diseases) 01/2018 - 01/2017
2	Pain (Aches) 11/2017 - 10/2012
2	Obesity 10/2016 - 11/2015
2	Choline Deficiency 10/2016 - 05/2010
2	Fibrosis (Cirrhosis) 01/2016 - 01/2016
2	HIV Infections (HIV Infection) 03/2015 - 06/2012
2	Breast Neoplasms (Breast Cancer) 01/2015 - 08/2013
2	Body Weight (Weight, Body) 08/2014 - 01/2012
2	Rheumatoid Arthritis 02/2013 - 08/2012
2	Scurvy (Scorbutus) 07/2011 - 01/2007
2	Hemangiosarcoma (Angiosarcoma) 04/2004 - 04/2003
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022
1	Hepatolenticular Degeneration (Wilson's Disease) 10/2020
1	Fatty Liver 10/2020
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 08/2020
1	Recurrent respiratory papillomatosis 01/2020
1	Lyme Disease (Disease, Lyme) 01/2020
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 12/2019

Drug/Important Bio-Agent (IBA)

26	VaccinesIBA 12/2022 - 04/2007
19	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2008
18	DNA VaccinesIBA 12/2022 - 04/2007
16	AntigensIBA 01/2020 - 04/2007
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2013
9	Choline (Choline Chloride)IBA 10/2019 - 04/2010
8	MicroRNAs (MicroRNA)IBA 08/2020 - 01/2012
7	Biological ProductsIBA 06/2022 - 02/2002
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 11/2015
6	Monoclonal AntibodiesIBA 01/2019 - 08/2013
6	riddelliineIBA 01/2012 - 07/2002
4	Long Noncoding RNAIBA 06/2022 - 01/2019
4	CytokinesIBA 01/2022 - 02/2013
4	Neoplasm Antigens (Tumor Antigens)IBA 01/2020 - 08/2013
4	AntibodiesIBA 01/2020 - 09/2015
4	A-Form DNA (A-DNA)IBA 01/2020 - 04/2007
4	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 02/2013 - 04/2011
4	DNA AdductsIBA 05/2008 - 04/2003
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2016
3	Messenger RNA (mRNA)IBA 04/2020 - 02/2014
3	Transcription Factors (Transcription Factor)IBA 12/2017 - 07/2010
3	CarcinogensIBA 01/2017 - 05/2015
3	InterferonsIBA 01/2016 - 10/2012
3	Pyrrolizidine AlkaloidsIBA 05/2008 - 04/2003
2	reluscovtogene ralaplasmidIBA 12/2022 - 01/2020
2	Connexin 43 (Connexin43)IBA 12/2019 - 08/2015
2	ChromatinIBA 01/2019 - 02/2014
2	Glycoproteins (Glycoprotein)IBA 11/2018 - 05/2014
2	Hemagglutinins (Hemagglutinin)IBA 01/2018 - 05/2014
2	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2018 - 01/2018
2	VGX-3100IBA 01/2018 - 11/2015
2	trimethyloxamine (trimethylamine N-oxide)IBA 01/2017 - 01/2017
2	Folic Acid (Vitamin M)FDA LinkGeneric 10/2016 - 11/2015
2	UbiquitinIBA 10/2015 - 05/2015
2	L-Gulonolactone OxidaseIBA 05/2013 - 07/2011
2	NucleoproteinsIBA 06/2012 - 09/2011
1	Antisense OligonucleotidesIBA 01/2022
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	SilverIBA 01/2021
1	naringeninIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Competitive Endogenous RNAIBA 01/2021
1	FlavonoidsIBA 01/2021
1	Combined VaccinesIBA 01/2021
1	roxadustatIBA 10/2020
1	CopperIBA 10/2020
1	3,3,5,5-tetramethyl-1-pyrroline N-oxide (TMPO)IBA 04/2020
1	Antisense RNA (Anti-Sense RNA)IBA 04/2020
1	Immunoconjugates (Immunoconjugate)IBA 01/2020
1	Cancer VaccinesIBA 01/2020
1	ProteomeIBA 01/2020
1	SurvivinIBA 01/2020

Therapy/Procedure

14	Therapeutics 10/2020 - 03/2013
7	Immunotherapy 01/2020 - 09/2008
2	Qigong (Qi Gong) 10/2018 - 01/2018
1	Moxibustion 08/2020